I am not constrained as much by the real world as I am motivated by what I like. The model railroad's time frame is modern day, sort of. 

The main operating roads are Santa Fe and CSX.  SP and WP (for the California Zephyr) have trackage rights to access the passenger facilities. Both roads share trackage in a Berea, OH-like town in the desert southwest foot hills.  There is also some mountain territory (upper level).

If you have a problem with Alco PAs sitting next to F40PHs, you might want to avoid the passenger locomotive photo section. If SD75s pulling Vert-A-Packs creates stress, proceed with caution.  Just saying.